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Given the numerous examples of astrocyte dysfunction in ALS, targeting astrocytes and astrocyte replacement are promising therapeutic approaches that have shown positive results in fALS animal models (Table 1)

Hereafter, 0.5 ml of non-clotted blood was transferred to a 2 ml vial and immediately centrifuged (3,000 g, 10 min), and the supernatant was subsequently removed

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Approximately 50 mg of tissue was collected for determination of GSH content, as previously described

Non-drinker and non-smoker with admitted voice abuse patterns particularly while coaching sport