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doi:10.1056/NEJMcp2009249 3

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"I think it's pretty good," he said of the opportunities

Casara Andre in conversation with Earth Buddy founder Sean Zyer

It not only eliminates ROS, enhances SOD and GSH-Px activity, and reduces malondialdehyde (MDA) levels (33), but also inhibits the TLR4-mediated MyD88 cascade, decreases p65 nuclear translocation and downstream inflammatory factors, and simultaneously activates the PI3K/Akt pathway, increasing the Bcl-2/Bax ratio and inhibiting caspase-3-mediated apoptosis (23)