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Price: 28.70 USD
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Description

J.LavineJ

de-Hoyos-Alonso MDC

It demonstrates potent anti-glioblastoma activity by: (1) blocking tumor invasion and cytokinesis (inducing polyploidy), (2) disrupting mitochondrial dynamics to elevate ROS and trigger ferroptosis, and (3) sensitizing tumors to radiotherapy/kinase inhibitors via ROS-driven PDGFR/mTOR pathway activation

Data were processed using GraphPad Prism 8.0 (GraphPad Software, San Diego, CA, USA) and the Michaelis constant ( K m ) and the maximum reaction rate ( V max ) of rHrGSTm1 were calculated by the Michaelis-Menten equation