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Directed evolution of LaccID: generation 2 For the second round of evolution, three libraries were generated using G1 (LacAnc100 + R121S) as the starting template

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However, the effect of oxidative and nitrosative stress is not restricted to the intracellular environment, as reactive species can cross cellular membranes and influence extracellular proteins

Prabhu, S., Molath, A., Choksi, H., Kumar, S

These observations were further supported by quantification, which indicated a decrease in the percentage of dead and apoptotic cells in Atp7b / :Prnp / hepatocyte populations compared to hepatocytes isolated from Atp7b / mice (Supplementary Fig