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Similarly, in patients with hypertension and hyperhomocysteinemia (18 males and 7 females, age 4065), reactive hyperemia is improved by 4 weeks oral L-arginine (Reule et al., 2017), administered in a mixture with pycnogenol, which itself activates eNOS (Fitzpatrick et al., 1998)

As with any procedure that involves inserting a needle into a vein, there are also risks of discomfort, bruising, infection or reaction at the site

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Supplementary information Supplementary Methods, Supplementary Figures 17 and Supplementary Tables 14 (PDF 598 kb) Rights and permissions About this article Cite this article Veeravalli, K., Boyd, D., Iverson, B