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conducted prospective and retrospective observational studies on the efficacy of the combination of duloxetine (DLX) and pregabalin (PGB) for the treatment of FM syndrome, and the possibility of additional benefits with the addition of the lipid signaling molecule palmitoylethanolamide (PEA) [59]

Structures of bacterial GGT and human GGT with inhibitors bound provide insight into the mechanism of inhibition of the enzyme (Ida et al., 2014, Terzyan et al., 2015, Wada et al., 2008, Wada et al., 2010)

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ROS are products of normal physiological activities and are a general term for a class of chemically active molecules and ions with high oxidative activity, which play important roles in cell signaling and tissue homeostasis ( 2 - ), peroxides (H 2 O 2 and LOOH), and free radicals (HO and LO)