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Description

The threshold Glide XP score and MMGBSA binding affinity values were set at -8 and -60 Kcal/mol respectively (based on docking scores with the substrate, glutathione) for the final screening of compounds

Georgescu, L., Vakkalanka, R

Huijbers IJ, Bin Ali R, Pritchard C et al (2014) Rapid target gene validation in complex cancer mouse models using re-derived embryonic stem cells

However, it is not possible to selectively inhibit DYRK1A expression

46 Laboratory findings The laboratory abnormalities found in DJS include elevation of conjugated and total bilirubin in the serum but normal aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase (ALP), and -glutamyltransferase (GGT) levels

Dig Liver Dis 2024;56:13121318.ArticlePubMed 22