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Others argue the opposite, that consistent low-dose activation maintains the beneficial signaling

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Schmitz et al, 1996

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For example, as tumors grow, they display strong patterns in their phenotype due to oxygen gradients 6 and Wnt signaling activators and inhibitors 7 , to the extent that these patterns are responsible for their resistance to chemo/radio therapies 8

This Superfacility project combines DIII-D and HPC resources to produce something greater than the sum of their parts just-in-time scientific results that would otherwise not be possible. Democratizing access to HPC resources The success of the DIII-D/NERSC Superfacility model is a victory for fusion energy research today, and it may also be a template for expanding the use of Superfacility and other IRI collaborations across the DOE lab complex