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Nature 542 , 450455 (2017)

Lipid deposition in worms was observed under a fluorescence microscope (BX53

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In a T cell-mediated chronic psoriasiform inflammation model, investigators observed the coexistence of pro-inflammatory macrophages expressing iNOS and alternatively activated macrophages expressing Arg1 in lesional tissues, suggesting that the partitioning of arginine metabolic pathways participates in regulating macrophage phenotypes and the intensity of inflammatory responses