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In transgenic Caenorhabditis elegans models of AD (CL2006 and CL4176), which express human A and exhibit paralysis as a phenotypic readout, OLE treatment reduced A deposition and delayed paralysis

Obesity The adipose tissue of mammals is divided into brown adipose tissue (BAT) and white adipose tissue (WAT)

Direct modulation of recombinant enzyme activity by graded hypoxia, iron chelation and cobaltous ions mirrored the characteristics of HIF induction in vivo , thereby fulfilling requirements for these HIF-prolyl hydroxylases to be oxygen sensors that regulate this transcription factor [9194]