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Garlic and onions are also rich in sulfur containing compounds that may help support glutathione production

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HO-1 mediates catalytic breakdown of heme, a potent pro-oxidant and pro-inflammatory molecule 465

Through the Fenton reaction, Fe + facilitates the conversion of hydrogen peroxide into highly reactive hydroxyl radicals and other ROS ( 2.1.1 Regional iron accumulation Significant alterations in iron distribution and accumulation occur in PD patient brains, a fact confirmed by postmortem studies and advanced neuroimaging techniques

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The Ki value for inhibition of TLGST with p CMB is 0.3 mM (Fig