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(2022) 3:119136.e8

Sample preparation and targeted LC-MS/MS Serum samples were prepared and analysed as previously described with slight modifications, as detailed in ESM Methods

Ethics declarations Competing interests M.R.H

Endoscopic mucosal dissection is the main treatment for early GC ( Angiogenesis is the formation of blood vessels form existing ones and it is also the basis of tumor proliferation, invasion, and metastasis in advanced GC ( In this review, in order to provide more personalized treatment plans for GC patients and provide a reliable theoretical basis for the treatment of GC with anti-angiogenic drugs, we systematically expounded the mechanism of angiogenesis on GC and summarized the results of registered clinical trials of anti-angiogenic targeted drugs for GC, as well as the response biomarkers of these drugs

New long-term data show Shingrix continues to provide high protection against shingles in adults aged 50 and over for more than a decade

Moreover, betaine was well tolerated and safe (Sookoian et al., 2017)