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Huang Y, Bai L, Yang Y, et al

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Bias correction for sequence-specific and GC content was enabled, and mapping validation was performed with selective alignment enabled

These changes were absent in high doses of onion extract (600 mg/kg) and only mild focal tubular necrosis was present in low doses (300 mg/kg) used in the experiment

In ischaemic stroke, experimental models have demonstrated that Huperzine A attenuates neuronal apoptosis by upregulating Bcl-2, downregulating pro-apoptotic Bax and p53, and inhibiting caspase-3 activation, thereby preserving mitochondrial membrane potential and promoting neuronal survival under hypoxic conditions [35, 44, 46]

C., Nemacheck, J