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It has been determined that free oxygen radical damage occurs in diseases such as bladder disease, prostate cancer, sepsis, myocardial infarction, stroke, perinatal hypoxic brain injury, glomerulonephritis, uveitis, various cancers and arthritis in laboratory, clinical and experiments 12,13,14,15,16,17,18

MPO ( R = 0.566, p = 0.044) and MMP-9 ( R = 0.441, p = 0.05) were negatively correlated and TIMP-1 ( R = 0.367, p = 0.089) was marginally positively correlated with duration of PTSD illness (see Figure 3)

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Brain metabolism modulates neuronal excitability in a mouse model of pyruvate dehydrogenase deficiency

Preclinical studies have demonstrated that curcumin downregulates pro-inflammatory cytokines such as TNF-, IL-6, and IL-17, while promoting regulatory T-cell induction