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As a naturally occurring tripeptide complexed with copper ions, GHK-Cu serves as an important compound in peptide-based biochemical research

The lid loops also undergo significant conformational changes resulting in Tyr182 inserting into the active site pockets

de Boer YS, van Gerven NMF, de Boer NKH, Mulder CJJ, Bouma G, van Nieuwkerk CMJ

AGEs promote oxidative stress by generating free radicals through interactions with transition metals such as iron and copper and by impairing antioxidant enzyme systems, thereby diminishing the cellular ability to eliminate ROS (Wei et al., 2013)

Stlhammar, 1990)

Detecting insulin resistance in polycystic ovary syndrome: purposes and pitfalls