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Curcumin attenuates inflammatory response and cognitive deficits in experimental model of chronic epilepsy

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10.1007/s12576-009-0065-3 97 SmedleyT.GrocottM

Therefore, there has to be certainty that all of the CAT has been inhibited before the administration of ethanol, and this may be the reason for the variability seen with this inhibitor when it is administered in vivo to determine the importance of CAT [31], because CAT has such a high activity that a large portion of it has to be inhibited before a drop in alcohol oxidation can occur [32,33]

Ferri, G

However, the precise molecular mechanisms underlying these alterations, particularly the relationship between GSSG reduction and the acute exacerbation of psychotic symptoms, require further investigation