glutathione for leukemia determines chronic myeloid vulnerability to an inhibitor of CMPK and TMPK Excited to share our #RedoxBiology

Excited to share our #RedoxBiology @sciencedirect @SFRBM article showing that #epigenetic defect in #leukemia creates vulnerability for #ferroptosis upon the use of #glutathione inhibitors, work led by Lucas Pontel @LucPontel @CarrerasIJC https: t.co iFSP1 is a Selective FSP1 Inhibitor Glutathione Independently Network of Cancer Research Glutathione is critical for NK cell mediated immunity: Cell Reports PDF) Emerging role of glutathione peroxidase 4 in myeloid cell lineage development and acute myeloid leukemia Glutathione overproduction mediates lymphoma initiating cells survival and has a sex dependent effect on lymphomagenesis Cell Death & Disease Sgc8 aptamer targeted glutathione responsive nanoassemblies containing Ara C prodrug for the treatment of acute lymphoblastic leukemia Nanoscale (RSC Publishing)

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