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Exp Neurobiol 24:4154

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These osteoclast defects appear to be cell-autonomous, as they could be recapitulated by culturing osteoclast precursors from the global IGF-I KO mice, which showed reduced ability to differentiate into mature osteoclasts (65)

Macromolecule Content Total Structure Weight: 304.62 kDa Atom Count: 22,586 Modeled Residue Count: 2,604 Deposited Residue Count: 2,616 Unique protein chains: 1 Experimental Data Method: X-RAY DIFFRACTION Resolution: 2.40 R-Value Free: 0.281 (Depositor), 0.273 (DCC) R-Value Work: 0.205 (Depositor), 0.202 (DCC) R-Value Observed: 0.209 (Depositor) Unit Cell : Software Package: Revision History (Full details and data files) Version 1.0: 2010-09-29 Type: Initial release Version 1.1: 2011-05-08 Changes: Version format compliance Version 1.2: 2011-07-13 Changes: Version format compliance Version 1.3: 2020-03-11 Changes: Derived calculations, Other Version 1.4: 2023-12-20 Changes: Data collection, Database references, Derived calculations, Refinement description

Pull the needle out and throw it and the syringe in a FDA-cleared sharps disposal container

The edge, node and average number of neighbor parameters all increase as the liver proceeds from period A to period C