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Interactions and who should take care Metformin and long-term proton pump inhibitors (acid-reducing medicines) can lower B12 absorption over time, so people on these may need their B12 status checked

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The exact dosage, however, should always be determined by a healthcare professional based on individual health assessments

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Renal hypoxia is the main stimulus for the production of erythropoietin by the juxtaglomerular apparatus, with this process being mediated by hypoxia-inducible factor (HIF