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It is known that COVID-19 is characterised by significant inflammation, whereby cytokine storms can lead to organ failure

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The cell membrane is composed of a phospholipid bilayer structure, and the phospholipid heads of the hydrophobic layer are easily damaged by oxidation 2

Studies employed Franz cell diffusion experiments and electrical impedance spectroscopy using human skin models to characterize pH-dependent permeation mechanisms

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doi:10.1016/j.ymgme.2009.12.015