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Description

The glutaminase inhibitor, telaglenastat (CB-839), has been tested in combination with carfilzomib and dexamethasone in relapsed and/or refractory MM, and newer inhibitors like DRP-104 (sirpiglenastat) are in solid tumor clinical trials (184186)

In contrast, compared to Cluster 1 and Cluster 3, these patients reported lower prevalences of many other primary symptoms, such as brain fog (71.1%), unrefreshing sleep (55.8%), memory problems (38.4%), feeling of weakness (39.8%), sore/painful muscles (25.8%), and insomnia (34.8%)