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Disclosures: Tatjana Reic: Nothing to Disclose, Ana Visic: Nothing to Disclose, Magda Pletikosa Pavic: Nothing to Disclose, Diana Nonkovic: Nothing to Disclose, Ivona Reic: Nothing to Disclose, Anna Mrzljak: Nothing to Disclose 945 CHARACTERISTICS OF PATIENTS WITH PRIMARY BILIARY CHOLANGITIS THAT RECEIVED TRANSIENT ELASTOGRAPHY AT A TERTIARY LIVER TRANSPLANT CENTER IN NORTHERN CALIFORNIA Vishwajit Kode 1 Sylvia Sudat 2 Yinwen Wang 3 Kidist Yimam 4 , 1 California Pacific Medical Center Department of Internal Medicine, 2 California Pacific Medical Center, Center for Health Systems Research, 3 California Pacific Medical Center Research Institute, 4 California Pacific Medical Center Department of Hepatology and Liver Transplant Background: Primary Biliary Cholangitis (PBC) is a rare, chronic cholestatic disease of the small intrahepatic bile ducts of autoimmune etiology

Here, we find EPOP can directly disrupt the dimeric form of PRC2.1 and thereby constrains its chromatin binding both in vitro and in vivo

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doi: 10.1016/j.phrs.2022.106369, 135