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Consistent with this finding, postmortem studies have reported markedly downregulated gene expression of antioxidant enzymes such as SOD1 and glutathione S-transferase in the hippocampus of BD patients, a finding that may relate to bipolar depression as the dominant phase [56]

doi: 10.3389/fonc.2025.1557233 Received 08 January 2025 Accepted 05 March 2025 Published 20 March 2025 Volume 15 - 2025 Edited by Fabiana Ourique, Universidade Federal de Juiz de Fora, Brazil Reviewed by Sivapar V