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This pattern mirrors the consequences of HHEX deficiency, where HHEX KO inhibits efficient pancreatic fate acquisition and promotes hepatic marker expression in hPSC-derived endoderm 7

Chusak, C., Thilavech, T

This data suggests that tazarotene can be an effective option for addressing hyperpigmentation in individuals with certain skin conditions, such as acne, particularly in black patients 3