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Ghashghaeinia M, Bobbala D, Wieder T, Koka S, Brck J, Fehrenbacher B, et al

This is why I actually don't, a little bit off-topic, like when people use testosterone pellets or any sort of pellet therapy, because you're exposing people to a concentration of hormones we would never, ever see in nature

Because it was not yet known whether sargramostim would be approved for additional indications and dosages, as indicated in the information provided by the applicant, and the available data did not provide enough information for CMS to determine whether Leukine had unique circumstances that would prompt an increase in the applicable percentage, we did not propose an increase in the applicable percentage for the drug in the CY 2025 PFS proposed rule, and stated the applicant may reapply in a future application cycle when more information becomes available

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Masino SA, Kahle JS

Studies document effects on 31.2% of human genes (approximately 4,000+ genes) with 50% expression change, suppressing RNA production in 70% of 54 genes overexpressed in metastatic colon cancer