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Nrf2 deficiency impairs the barrier function of mouse oesophageal epithelium

Arch Gynecol Obstet 2011;284:1367-73

There is a great deal of evidence suggesting that DNA methylation defects are associated with ASDs, and the role of the methylenetetrahydrofolate reductase (MTHFR) gene in folate metabolism may contribute to epigenetic mechanisms that modify complex gene expression, thus causing autism