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The study planned to include 200 patients with type 2 diabetes who were not on any antidiabetic drugs in the 90 days prior to Visit 1 (except in certain clinical situations, such as acute illness, hospitalization, or elective surgery, short-term (14 days) use of insulin)

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In the ischemia-reperfusion (I/R)-AKI model, the E3 ligase Trim21 is highly expressed, which modulates AKI by ubiquitinating degradation of glutathione peroxidase 4 (GPX4)

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Cross-talk between Wnt signaling pathways in human mesenchymal stem cells leads to functional antagonism during osteogenic differentiation