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In aerobic organisms, the main reactive species are ROS (Halliwell and Gutteridge, 2015), but additional families include reactive nitrogen species (RNS) and reactive sulphur species (RSS), which interact with or enhance ROS generation (Figure 2)

Research shows that intracerebroventricular injection of soluble A-42 in wildtype rats and mice induces depressive-like behavior, as shown by increased immobility in FST (Ledo et al., 2013)

With the admission of vitamin E, paraoxonase 1 protein has expanded in the blood, showing a decline in OS and protecting the lipids from oxidation (67)

Recent studies demonstrate promising synergistic effects when combining EGCG with established treatments for neurodegenerative disorders

The c-Met receptor tyrosine kinase inhibitor MP470 radiosensitizes glioblastoma cells

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