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Int Urol Nephrol

If your fridge runs warm (above 8 degrees), the degradation rate increases

Renal outcomes and all-cause death associated with sodium-glucose co-transporter-2 inhibitors versus other glucose-lowering drugs (CVD-REAL 3 Korea)

The conservative 1mg starting dose allows assessment of individual tolerance before increasing

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It may be relevant to oxidative and acidbase stress, but it should not be described as directly removing creatinine or reversing kidney failure without stronger evidence