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Graphical Abstract Similar content being viewed by others Introduction Metformin, the primary treatment for type 2 diabetes, is largely well tolerated but can cause vitamin B 12 deficiency in 5.822% [1, 2] of patients

In contrast to Wnt7a deficient mice, Wnt5a null mice display clear PCP defects with a slightly shortened and broader cochlea consisting of additional rows of hair cells along its entire length, especially towards the apical end

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