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The presence of other components in the formulation did not interfere with the estimation of the three drugs

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Once fructose-1,6-bisphosphate has formed, the commitment to downstream glycolysis is complete, although subsequent formation of glyceraldehyde-3-phosphate may cycle back to the non-oxidative phase of the pentose phosphate pathway (Fig

We estimated the standard deviation (SD) of 0.2 for M-values based on empirical observations from our dataset and typical variability in similar methylation studies