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Figure 1 DNA methyl transferases (DNMTs) are a family of enzymes that catalyze the transfer of the methyl group to the DNA

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Leptin inhibits the release of the orexigenic neuropeptides orexin and melanocortin-concentrating hormone (MCH) in the lateral hypothalamic area (LHA) through the release of CART and melanocyte-stimulating hormone (-MSH)