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For instance, astragaloside IV, a natural compound extracted from Astragalus , showed neuroprotective effects through calcium-sensing-receptor-mediated apoptosis

[DOI] [PMC free article] [PubMed] [Google Scholar] 1021.Grandl G., Wolfrum C

Taken together, these observations support the idea that phenotypic alterations during T2DM may depend strongly on obesity status and energy expenditures on a molecular level, potentially in response to changes in the transcriptome