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Additionally, through a structural alignment with drDDC and pig DDC, a conserved histidine (H192) was also identified, which has been reported to interact with the pyridine ring of PLP

These molecules possess a very favorable ADMET profile and will also be considered for further exploration in anticancer research

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Stevens, D., Burman, D., Strelling, M

Although acetyltransferases such as p300 exhibit general acyl transfer activity, no bona fide lactyltransferases have been identified