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Elesclomol (ES) and Disulfiram (DFS) induce apoptosis by transporting copper ions into cells and mitochondria, resulting in the oligomerization of dihydrolipoamide s-acetyltransferase, decreased stability of Fe-S clusters and interaction with Npl4 (Reeder et al., 2011)

Here, we summarize the research history, origins, properties, molecular regulations, mechanisms for therapeutic resistance, and treatment strategies of CSCs

The nanapeptides (nine amino acids), oxytocin and vasopressin are important animal peptide hormones

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The deletion was validated using the cycloheximide sensitivity assay (Figure S4)

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