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At higher levels, vitamin C acts as a pro-oxidant

Nat Commun 10:1731

The functional activity of FVII from supernatants of iPSC-HO was assessed by two methods: a) western blotting after activation with tissue factor (TF, STA Neoplastin) and CaCl 2 and incubation with antithrombin (AT), purified from human plasma, (Grifols, Spain) and unfractionated heparin (Hospira) to measure the ability of FVII to become active and form a complex with AT

After the use of this substance on male rabbits, a reduction of the testicular and epididymal mass was observed, which implies that this substance might cause testicular atrophy

Several factors, including fish species, age, and water quality, may vary Mn toxicity in fish [136]