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Plant Cell 25, 29442957

The clinical landscape of cutaneous neurofibromas in neurofibromatosis type 1 Rare Dis Orphan Drugs J

By elevating expression of TNFAIP3, a gene already associated with reduced susceptibility to RA, the pro-inflammatory macrophage that is critical to maintenance of the inflammatory state in RA is reprogrammed to a quiescent or tolerant state

doi: 10.1172/JCI200215606 8 KarasawaTSteygerPS

Proline functions as a compatible osmolyte, stabilizing proteins and membranes while directly scavenging reactive oxygen species (ROS) (Hayat et al