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In fact, diabetes induces an alteration in the activity of glutathione peroxidase and reductase to maintain a normal GSH level in order to avoid the increase of nitric oxide and the risk of thrombosis

To view a copy of this license, visit About this article Cite this article Ortega, M.A., lvarez-Mon, M.A., Garca-Montero, C

Antibodies against proteins that aggregate in neurodegenerative diseases, such as Alzheimers and Parkinsons, are being developed for clinical use and have even shown potential in ALS cellular and mouse models 27,47,48,49,50,51,52

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The EAT protocol includes, amongst others, the use of hamster-derived S9-fraction for preparation of S9-mix, as it contains higher levels of certain CYPs relevant for metabolic activation of NAs, compared to the standard rat S9-fraction