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The maintenance dose is often the same as the loading dose, 1,000 mcg per injection , but its given less often

Common side effects may include mild irritation at the injection site, water retention, or headaches

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doi:10.1056/NEJMoa2109730

Protecting lean mass during cagrilintide use Until definitive data emerges, established principles for lean mass preservation apply: Resistance training at least 2 to 3 sessions per week provides the strongest stimulus for muscle preservation Protein intake of 0.7 to 1.0 grams per pound of body weight daily, even when appetite is suppressed Adequate total calories avoiding deficits greater than 500 to 750 calories below maintenance Creatine supplementation may provide additional support for muscle maintenance during caloric restriction For researchers specifically interested in maintaining muscle while losing fat, our guide on the best peptides for muscle growth covers complementary approaches

The same commentary urges patients to run from the doctors recommending this compound , given its unapproved status