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Pregabalin had a smaller positive effect on sleep quality, while other medications showed no or uncertain effects on sleep, and drug therapies in general were associated with more adverse side effects

Monthly or even quarterly depot injections of GLP-1 agonists are in development

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Intra-articular steroids could be prescribed in these cases (61)

IFATS collection: adipose stromal cell differentiation is reduced by endothelial cell contact and paracrine communication: role of canonical Wnt signaling