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Since the peptides have a short half-life because of their small size, they can easily get degraded by the enzymes present inside the human body and filtered out by the kidneys

The literature that met the inclusion criteria advanced to full-text evaluation

Human trials remain scarce

Proc Natl Acad Sci 104:1183211837 Dias RB, de Arajo TBS, de Freitas RD et al (2018) -Lapachone and its iodine derivatives cause cell cycle arrest at G2/M phase and reactive oxygen species-mediated apoptosis in human oral squamous cell carcinoma cells

Exercise prevents raphe nucleus mitochondrial overactivity in a rat depression model

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