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Description

Infiltration by monocytes of the CNS and its role in multiple sclerosis: reflections on therapeutic strategies

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TZ: Writing review & editing, Investigation

Hepatology 25 , 14571461 (1997)

406,407 Interestingly, IDH1 mutants compete for NADPH to synthesize 2-HG with other pathways that are critical for cell viability, resulting in further disruption of cellular metabolism and redox homeostasis in tumorigenesis