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Calcium channel Calcium is a critical regulator of cardiac function by maintaining cardiac excitation-contraction coupling, and disturbances in cardiac calcium regulation are a major contributor to left ventricular dysfunction in iron overload cardiomyopathy ( 2+ channels participate in iron uptake into cardiomyocytes (61)

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Whether vaccines, and particularly adjuvanted (killed) vaccines, are more likely to induce FISS than other injections remains unclear, but because adjuvants promote local inflammation, they may have a role in tumorigenesis and WSAVA vaccination guidelines state non-adjuvanted vaccines should be administered to cats wherever possible (Day et al, 2016)