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Furthermore, the scatter plot distributions indicated potential linear associations within all three analysis groups (Fig

58,59 Interactions between innate immune components such as Toll-like receptors (TLRs) and endogenous danger-associated molecular patterns (DAMPs) or pathogen-associated molecular patterns induce nuclear factor-B (NF-B)-mediated inflammation 59 while also promoting renal apoptosis and fibrosis

Functionally, Kla plays a fundamental role in physiology, such as somatic cell reprogramming, as well as embryonic, neural, and cochlear development, by regulating gene expression, cell cycle progression, and signal transduction