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This represents a critical advantage over conventional antidepressants that typically require 2-6 weeks to produce therapeutic effects in humans

doi:10.1016/j.pneurobio.2021.102127 [4] Dmitrieva NO, Almeida DM, Dmitrieva J, Loken E, Pieper CF

Upon internalization, pyrophosphodiester passes through the endosome-lysosome pathway, which undergoes a two-step enzymatic linker cleavage, releasing first the payload-monophosphate molecule, followed by the free payload

S., Akil H

As I said, I think that's an open question, but open to hearing about any research which would shed light on that

Commensal bacteria protect against food allergen sensitization