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However, as with other lipid-based nanosystems, key challenges remain, including ensuring long-term formulation stability, evaluating safety with repeated topical application, and scaling up production for clinical-grade batches [123, 124, 134]

Instead, glycolic acid works by gently loosening the dead layer of skin on the surface, revealing the glowing epidermis below. Since glycolic acid helps slough off the top layer of dead skin cells, it also allows for better penetration of your face treatment products, making it effective in treating issues with skin discoloration, acne and rough texture

Studies suggest this may be linked to vitamin A deficiency, which influences serotonin processing [5]

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Available at: (Accessed on 5th January 2026)