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4 integrates extracellular stress and growth cues to regulate cell-cycle progression, apoptosis, and differentiation, and frequently cooperates with NF-B signaling to promote cancer cell survival and metastasis

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GGT activity (d) (n = 6 technical replicates from 3 independent experiments) and cell numbers (e) (n = 3 technical replicates for Cys 2 -free or n = 6 technical replicates for Control or Cys 2 -free + GSH from 3 independent experiments) for cells grown in control (208 M cystine

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