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Based on current scientific literature, the areas where MOTS-c shows the most promising effects include: - Improved insulin sensitivity and glucose metabolism: Multiple animal studies have demonstrated improvements in glucose tolerance and insulin sensitivity with MOTS-c treatment - Metabolic health and weight management: By activating AMPK and enhancing fat oxidation, MOTS-c may help achieve/maintain healthier body composition, particularly in the context of diet-induced or age-related metabolic decline - Exercise capacity and endurance: MOTS-c has been shown to improve exercise capacity in animal studies, possibly due to mitochondrial efficiency as well as enhanced muscle metabolism - Healthy aging: MOTS-c is one of the well-studied peptides when it comes to longevity

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10.1016/j.neuropharm.2010.10.029 Neuropharmacology 231 MillerK

Vitamin C plays a key role in boosting Collagen synthesis, which keeps your skin plump and youthful

This is significant because the melatonin synthesis pathway runs from tryptophan to serotonin to N-acetylserotonin to melatonin

Another autophagy inhibitor 3-MA also produced rescuing effects but to a smaller extent in erastin-treated cells