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Description

This condition is also known as benign essential tremor, familiar tremor, hereditary tremor, benign familial tremor or shaky hand syndrome

10.1016/j.neuint.2016.09.008 Neurochem

The included studies involved 461 participants comprising 233 participants in the experimental group and 228 participants in the control group

Biosci Biotechnol Biochem 61:19771980

Several factors have been identified related to the pathogenesis of ALS: OS, mitochondrial dysfunction, neuroinflammation, excitotoxicity due to an increase in the neurotransmitter glutamate, defect in axonal transmission and in the metabolism of RNA, apoptosis, cytoskeletal abnormalities, disruption of membrane trafficking, endoplasmic reticulum stress, protein misfolding and aggregation (Papadimitriou et al., 2010