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Apart from bacterial translocation due to a leaky gut, new research has shown that microbiota in the dental-brain axis, uterus-brain axis, and skin-brain axis may be involved in MDD [128, 197, 198]

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The protein and mRNA expression of RIPK3 were tested by immunoblotting (left) and qRCR (right) analyses (n = 3)

Studies on the changes of pharmacokinetics behaviors of phytochemicals and the influence on endogenous metabolites after the combination of Radix Bupleuri and Radix Paeoniae Alba based on multi-component pharmacokinetics and metabolomics

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Furthermore, we evaluated the potential effect of EBV/LMP exposure on the ER activation, found that ER specific blockade PHTPP had no effect on EBV/LMP1 exposure-mediated ER upregulation (see Supplementary Figure S2A), while it completely diminished EBV/LMP1 exposure-mediated cell proliferation (see Supplementary Figure S2B)